Coronary disease & ACS

Dobutamine stress cardiac magnetic resonance role in patients with anomalous aortic origin of coronary arteries

Eur Heart J Cardiovasc ImagingPublished single-centre observational study

Authors' conclusion

dsCMR is a reliable test for the evaluation of myocardial ischaemia in AAOCA, especially for those with intramural course, ischaemic LGE, and previous ACS episodes. Although rare, older patients may have a myocardial ischaemic scar without alteration of ventricular function.

Study context

Population
Anomalous Aortic Origin of Coronary Arteries (AAOCA) patients who underwent dobutamine-stress cardiac magnetic resonance (dsCMR), regardless of age, enrolled from 2015 to 2024AAOCA patients who underwent dsCMR
Participants
100 patients
Outcome
Inducible myocardial ischaemia (positive dsCMR)

Main finding

As reported in the abstract

dsCMR positive

14 cases

Observational data: associations, not effects.

Further findings

Factors associated with inducible ischaemia

Intramural course, ischaemic late gadolinium enhancement (LGE) and history of acute coronary syndrome (ACS) significantly associated with inducible ischaemia

Ischaemic LGE within the AAOCA territory

Patients with small areas of ischaemic LGE
Nine patients (9%)
Patients with ischaemic LGE were older with a higher incidence of arterial hypertension, smoking habits and previous ACS episodes

Original publication

Dobutamine stress cardiac magnetic resonance role in patients with anomalous aortic origin of coronary arteries. Eur Heart J Cardiovasc Imaging. Published 5 May 2025. doi:10.1093/ehjci/jeaf134

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