Valvular & structural heart diseaseCohort study
Double Inflation (“Double Tap”) on Valve Expansion and Short-Term Outcomes After the Latest-Generation Balloon-Expandable TAVR
- Prospective single-group study
- consecutive patients
Authors' conclusion
Routine postdilatation of the latest generation balloon-expandable valve, when clinically and anatomically feasible, appeared safe and improved frame expansion and foreshortening.
Study context
- Population
- Patients undergoing S3UR TAVR for native AS, January 2024 to March 2025206 screened
- Participants
- 200 patients
- Exposure
- Routine postdilatation of S3UR
- Routine postdilatationn = 200
- Outcome
- Frame expansion, foreshortening and short-term outcomes after routine postdilatation
- Follow-up
- Median 30 days
Main finding
As reported in the abstract
Frame expansion and foreshortening
- All S3UR valves significantly underexpanded, especially at midframe, irrespective of size
- Significant expansion and foreshortening after postdilatation
Observational data: associations, not effects.
Further findings
Mean valve gradient · median 30 days
- Mean valve gradient (± SD)
- 10.7 ± 4.2 mm Hg
Frame expansion and foreshortening
- All S3UR valves significantly underexpanded, especially at midframe, irrespective of size; significant expansion and foreshortening after postdilatation
All-cause mortality · median 30 days
- All-cause mortality
- 1.5% (3 of 200)
Greater than mild paravalvular leak · median 30 days
- Patients with greater than mild paravalvular leak
- 0
Safety
In-hospital adverse events
- In-hospital adverse events
- 0
Stroke · median 30 days
- Stroke
- 3.0% (6 of 200)
Original publication
Double Inflation (“Double Tap”) on Valve Expansion and Short-Term Outcomes After the Latest-Generation Balloon-Expandable TAVR. JACC Cardiovasc Interv. Published 16 November 2025. doi:10.1016/j.jcin.2025.11.004
Summarised from the published abstract; every number is checked against it