Hypertension

Echocardiographic Differences in Women Across Subtypes of Hypertensive Disorders of Pregnancy

JACC AdvPublished Retrospective cohort study

Authors' conclusion

LV remodeling and diastolic filling abnormalities are more common in HDP and are most evident in SPE and PRE.

Study context

Population
Women aged ≥18 years with an echocardiogram during or within the first year of pregnancy427 cases
Participants
706 women
Exposure
Hypertensive disorders of pregnancy (HDP) subtypes vs normotensive pregnant controls
  • Gestational hypertensionn = 57
  • Preeclampsia (PRE)n = 291
  • Superimposed preeclampsia (SPE)n = 79
  • Normotensive controlsn = 279reference
Outcome
Echocardiographic biventricular structure and function
Follow-up
During or within the first year of pregnancy
Methodological detailsintegrated health network
  • Integrated health network

Main finding

As reported in the abstract

Adjusted echocardiographic parameters (LV mass index, E/e')

Adjusted β

14.45

95% CI 9.00–19.90P < 0.001

Left ventricular (LV) mass index

Adjusted β

2.97

95% CI 2.27–3.68P < 0.001

E/e'

Observational data: associations, not effects.

Original publication

Echocardiographic Differences in Women Across Subtypes of Hypertensive Disorders of Pregnancy. JACC Adv. Published 29 November 2023. doi:10.1016/j.jacadv.2023.100725

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