Arrhythmias & electrophysiology
Effects of Extreme Humidity and Heat on Ventricular Arrhythmia Risk in Patients With Cardiac Devices
Main finding · VT/VF with extreme humidityResult — go to the resultAdjusted odds ratio 1.23 95% CI 1.00–1.51Authors' conclusion
In patients with preexisting cardiovascular disease, exposure to extreme humidity increased VT/VF risk, especially among vulnerable individuals, disadvantaged communities, and urban areas with less green space.
Study context
- Population
- Patients with pacemakers and defibrillators in North Carolina (2010–2021)484,988 person-days
- Participants
- 5,944 patients
- Comparison
- Extreme humidity and high temperature vs non-extreme warm-season conditions
- Outcome
- VT/VF events
- Follow-up
- 7 days following exposure
Methodological detailsdistributed lag nonlinear models
- Distributed lag nonlinear models
Main finding
VT/VF with extreme humidity
Adjusted odds ratio
1.23
95% CI 1.00–1.51
Extreme humidity and high temperaturevs non-extreme warm-season conditions
aOR 1.23 (95% CI 1.00–1.51)
As reported in the abstract
Further findings
Humidity-associated VT/VF, by patient subgroup
| aOR (95% CI) | ||
|---|---|---|
| Male | 1.38 (1.08–1.76) | |
| Age 67 to 75 years | 1.65 (1.16–2.35) | |
| CAD | 1.79 (1.25–2.57) | |
| HF | 1.72 (1.2–2.46) | |
| Diabetes | 3.01 (1.99–4.56) | |
| Hypertension | 2.06 (1.48–2.88) | |
| Prior MI | 1.75 (1.23–2.48) | |
| 0.20.5125Adjusted odds ratio (log scale) |
VT/VF risk, by community and built environment
| aOR (95% CI) | ||
|---|---|---|
| High socioeconomic deprivation | 1.83 (1.28–2.62) | |
| High income inequality | 1.56 (1.19–2.04) | |
| Urban areas with less greenspace | 1.29 (0.93–1.78) | |
| 0.20.5125Adjusted odds ratio (log scale) |
High temperatures and VT/VF
- High temperatures were not associated with VT/VF
Original publication
Effects of Extreme Humidity and Heat on Ventricular Arrhythmia Risk in Patients With Cardiac Devices. JACC Adv. Published 13 December 2024. doi:10. 1016/ j. jacadv. 2024. 101463
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