Arrhythmias & electrophysiology

Effects of Extreme Humidity and Heat on Ventricular Arrhythmia Risk in Patients With Cardiac Devices

JACC AdvPublished Case time-series study

Main finding · VT/VF with extreme humidityResult — go to the resultAdjusted odds ratio 1.23 95% CI 1.00–1.51

Authors' conclusion

In patients with preexisting cardiovascular disease, exposure to extreme humidity increased VT/VF risk, especially among vulnerable individuals, disadvantaged communities, and urban areas with less green space.

Study context

Population
Patients with pacemakers and defibrillators in North Carolina (2010–2021)484,988 person-days
Participants
5,944 patients
Comparison
Extreme humidity and high temperature vs non-extreme warm-season conditions
Outcome
VT/VF events
Follow-up
7 days following exposure
Methodological detailsdistributed lag nonlinear models
  • Distributed lag nonlinear models

Main finding

VT/VF with extreme humidity

Adjusted odds ratio

1.23

95% CI 1.00–1.51

Extreme humidity and high temperaturevs non-extreme warm-season conditions
aOR 1.23 (95% CI 1.00–1.51)

As reported in the abstract

Further findings

Humidity-associated VT/VF, by patient subgroup

aOR (95% CI)
Male1.38 (1.08–1.76)
Age 67 to 75 years1.65 (1.16–2.35)
CAD1.79 (1.25–2.57)
HF1.72 (1.2–2.46)
Diabetes3.01 (1.99–4.56)
Hypertension2.06 (1.48–2.88)
Prior MI1.75 (1.23–2.48)

VT/VF risk, by community and built environment

aOR (95% CI)
High socioeconomic deprivation1.83 (1.28–2.62)
High income inequality1.56 (1.19–2.04)
Urban areas with less greenspace1.29 (0.93–1.78)

High temperatures and VT/VF

High temperatures were not associated with VT/VF

Original publication

Effects of Extreme Humidity and Heat on Ventricular Arrhythmia Risk in Patients With Cardiac Devices. JACC Adv. Published 13 December 2024. doi:10.1016/j.jacadv.2024.101463

Composed by AI from the published abstract and checked against it. How Briefs are made →

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