Arrhythmias & electrophysiology
Efficacy of percutaneous stellate ganglion block according to ventricular arrhythmia cycle length: A post hoc subanalysis of the STAR study
Authors' conclusion
PSGB is an effective treatment of electrical storm in patients with all types of ventricular arrhythmias. However, its effectiveness was more pronounced in patients with VF.
Study context
- Population
- Patients with electrical storm treated with percutaneous stellate ganglion block (PSGB)PSGBs in 112 patients
- Participants
- 139 patients
- Comparison
- PSGB efficacy by ventricular arrhythmia type and cycle length
- Ventricular fibrillation (VF)n = 51 procedures
- Fast ventricular tachycardia (VT)n = 44 procedures
- Slow VTn = 44 procedures
- Primary endpoint
- Number of treated arrhythmic episodes (antitachycardia pacing or DC shocks) in the hour after PSGB vs the hour before
- Follow-up
- 1 hour before vs 1 hour after PSGB
Methodological detailspost hoc subanalysis, multicentre
- Post hoc subanalysis
- Multicentre
Primary result
As reported in the abstract
Treated arrhythmic episodes, hour after vs hour before PSGB
| Group | Value | Hour before |
|---|---|---|
| VF | 0 (range 0–1) | 5 [2-8] |
| Fast VT | 0 (range 0–0) | 1 [0-6.5] |
| Slow VT | 0 (range 0–0) | 1 [0-4.5] |
Value
VF0 (range 0–1)
Fast VT0 (range 0–0)
Slow VT0 (range 0–0)
Hour before
VF5 [2-8]
Fast VT1 [0-6.5]
Slow VT1 [0-4.5]
- VF: P < 0.001 — hour after vs hour before
- Fast VT: P < 0.001 — hour after vs hour before
- Slow VT: P = 0.001 — hour after vs hour before
Further findings
Reduction in ATP sequences or DC shocks across groups
- Significant trend across groups (Jonckheere-Terpstra)
- P < 0.001
- Significant difference slow VT vs VF and fast VT vs VF; not slow VT vs fast VT
- VF independently associated with probability of reduction of treated events after PSGB
Original publication
Efficacy of percutaneous stellate ganglion block according to ventricular arrhythmia cycle length: A post hoc subanalysis of the STAR study. Heart Rhythm. Published 15 November 2024. doi:10.
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