Arrhythmias & electrophysiology

Impact of an Organized Treatment Pathway on Management of Atrial Fibrillation: The ER2EP Study

JACC AdvPublished Prospective observational registry

Authors' conclusion

This study provides evidence that having an organized pathway from the emergency department for AF patients involving electrophysiology services can improve early access to definitive therapies and clinical outcomes.

Study context

Population
Patients with atrial fibrillation (AF) seen in the emergency room
Participants
500 patients
Exposure
Organized AF treatment pathway vs routine care
  • ER2EPn = 250
  • Controln = 250reference
Outcome
Time to ablation, time to anticoagulation initiation, antiarrhythmic drug initiation
Methodological detailsmulticentre, multivariable regression
  • Multicentre
  • Multivariable regression

Main finding

As reported in the abstract

GroupTime to ablationTime to anticoagulation initiationAntiarrhythmic drug initiation
ER2EP56 ± 50.9 days2.1 ± 1.6 days4.8 ± 7.1 days
Control183.3 ± 109.5 days19.7 ± 35 days24.7 ± 44.4 days

Time to ablation

ER2EP56 ± 50.9 days
Control183.3 ± 109.5 days

Time to anticoagulation initiation

ER2EP2.1 ± 1.6 days
Control19.7 ± 35 days

Antiarrhythmic drug initiation

ER2EP4.8 ± 7.1 days
Control24.7 ± 44.4 days
  • ER2EP vs Control: P < 0.001 — time to ablation
  • ER2EP vs Control: P < 0.001 — time to anticoagulation initiation
  • ER2EP vs Control: P < 0.001 — antiarrhythmic drug initiation

Observational data: associations, not effects.

Further findings

Length of stay

P = 0.002

Original publication

Impact of an Organized Treatment Pathway on Management of Atrial Fibrillation: The ER2EP Study. JACC Adv. Published 21 March 2024. doi:10.1016/j.jacadv.2024.100905

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