Heart failure & cardiomyopathies
Extended ambulatory electrocardiographic (ECG) monitoring enhances identification of higher-risk ventricular tachyarrhythmias in patients with hypertrophic cardiomyopathy
Performance · NSVT detectionResult — go to the resultFold greater diagnostic yield 2.7Authors' conclusion
In HCM, NSVT episodes are frequent; however, in most patients, both NSVT and higher-risk NSVT were not detected during initial 48 hours and were confined solely to extended monitoring period.
Study context
- Population
- Consecutive patients with hypertrophic cardiomyopathy (49 ± 12 years)
- Participants
- 236 patients
- Comparison
- Extended 14-day vs initial 48-hour ambulatory ECG monitoring
- Outcome
- Diagnostic yield of NSVT
- Follow-up
- 48 hours vs 14 days
Methodological detailsconsecutive patients
- Consecutive patients
Performance
NSVT detection
Fold greater diagnostic yield
2.7
P < 0.001
Events by group
14 days
48%
114 events
≤ 48 hours
42
events
As reported in the abstract
- Initial nonsustained ventricular tachycardia (NSVT) only during extended monitoring (3 to 14 days)
- 72 (63%)
- Initial NSVT ≤ 48 hours, of 114 with NSVT
- 42 (37%)
Further findings
| Outcome | Fold greater diagnostic yield | P value |
|---|---|---|
| Higher-risk NSVT (≥ 8 beats, > 200 bpm, ≥ 2 runs in consecutive 2-day period) | 3 | P < 0.001 |
NSVT characteristics · 14 days
- Median runs of NSVT
- 2
- Median length of NSVT (range: 3 to 67)
- 7 beats
- Median rate (range 120 to 240 bpm)
- 167 bpm
Original publication
Extended ambulatory ECG monitoring enhances identification of higher-risk ventricular tachyarrhythmias in patients with hypertrophic cardiomyopathy. Heart Rhythm. Published 20 September 2024. doi:10.
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