Arrhythmias & electrophysiology
Extrastimuli-assisted functional mapping improves ventricular tachycardia ablation outcomes: A systematic review, meta-analysis, and meta-regression
Authors' conclusion
Functional mapping was demonstrated to be safe for VT ablation. Dynamic functional mapping independently associated with reduced postablation recurrence rates without significantly increasing procedure duration.
Study context
- Population
- Patients undergoing functional mapping-assisted ventricular tachycardia (VT) ablation
- Participants
- 674 patients16 studies
- Comparison
- Dynamic and static mapping approaches
- Outcome
- Procedure duration
Methodological detailsrandom effects models, subgroup analysis
- Random effects models
- Subgroup analysis
Pooled result
As reported in the abstract
- Dynamic mapping vs Static mapping: P = 0.520
Further pooled results
| Outcome | P value |
|---|---|
| VT recurrence rateDynamic mapping vs Static mapping · significantly lower with dynamic mapping | P < 0.010 |
| VT recurrence rateDynamic mapping vs Static mapping | P = 0.005 |
- VT recurrence rate: meta-regression adjusted for ischemic cause and left ventricular ejection fraction; lower recurrence with dynamic mapping
Study and patient characteristics
- Follow-up
- 6 to 38.1 ± 29.7 months
- Ischemic cause
- 490 (72.7%) patients
- Left ventricular ejection fraction
- 25% ± 10% to 41.5% ± 13.8%
- Studies using dynamic mapping
- 9 (57.1%)
- Studies using static techniques
- 6 (37.5%)
- Studies using a mixed approach
- 1 (6.3%)
Safety
| Outcome | P value |
|---|---|
| Complication incidenceSimilar | P = 0.110 |
Original publication
Extrastimuli-assisted functional mapping improves ventricular tachycardia ablation outcomes: A systematic review, meta-analysis, and meta-regression. Heart Rhythm. Published 4 April 2025. doi:10.
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