Valvular & structural heart disease
Feasibility and reliability of comprehensive three-dimensional transoesophageal echocardiography screening process for transcatheter mitral valve replacement
Authors' conclusion
3D-TOE appraisements showed good correlations with CT measurements and high accuracy to predict TMVR screening success.
Study context
- Population
- Transcatheter mitral valve replacement (TMVR) candidates undergoing pre-procedural computed tomography (CT) and 3D-TOE
- Participants
- 72 candidates
- Exposure
- 3D-TOE vs CT for TMVR screening
- Outcome
- Feasibility and reliability of comprehensive 3D-TOE screening vs CT (MA, AML length, native LVOT, predicted neo-LVOT; TMVR eligibility)
Methodological detailsconsecutive patients, Final suitability decided by valve manufacturer on CT measurements and clinical conditions
- Consecutive patients
- Final suitability decided by valve manufacturer on CT measurements and clinical conditions
Main finding
As reported in the abstract
- Adequate image quality for 3D-TOE analysis
- all patients
- Anterior mitral leaflet (AML) length correlation
- r = 0.97
- MA area correlation
- r = 0.90
- MA perimeter correlation
- r = 0.68
- MA anteroposterior diameter correlation
- r = 0.88
- MA posteromedial-anterolateral diameter correlation
- r = 0.74
- Native left ventricular outflow tract (LVOT) area correlation
- r = 0.86
- Predicted neo-LVOT area correlation
- r = 0.96
- Agreement on TMVR eligibility (Cohen kappa)
- 0.83, P < 0.001
Observational data: associations, not effects.
Original publication
Feasibility and reliability of comprehensive three-dimensional transoesophageal echocardiography screening process for transcatheter mitral valve replacement. Eur Heart J Cardiovasc Imaging. Published 17 February 2023. doi:10.
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