Arrhythmias & electrophysiology
Focal pulsed field ablation in complex atrial tachycardia: First clinical experience and 1-year outcome
Authors' conclusion
Focal PFA of complex AT substrates was safe and efficient. Acute procedural success was 100%. After 1 year, the majority of patients were in sinus rhythm. A minority of recurrences was caused by insufficient PFA lesion creation.
Study context
- Population
- Patients with complex atrial tachycardia (AT), most (32/34) after ≥1 prior radiofrequency ablation, 2022–2023
- Participants
- 34 patients
- Outcome
- Feasibility, safety and long-term outcome (recurrence of any AT)
- Follow-up
- Mean 340.9 ± 130.1 days
Methodological detailssingle-centre, consecutive patients, 51 linear lesions created and 12 pulmonary veins (re)isolated
- Single-centre
- Consecutive patients
- 51 linear lesions created and 12 pulmonary veins (re)isolated
Main finding
As reported in the abstract
Acute procedural success in all patients
100%
Recurrence of any AT after mean follow-up of 340.9 ± 130.1 days
15 patients
44.1%
Observational data: associations, not effects.
Further findings
Procedural metrics
- Mean procedural duration
- 102.7 ± 30.3 minutes
- Left atrial dwell time
- 75.0 ± 24.7 minutes
- Mean fluoroscopy duration
- 8.7 ± 5.3 minutes
Lesions created
- Linear lesions
- 51
- Pulmonary veins (re)isolated
- 12
Findings at reablation
- Reablations
- 9
- Gaps in previously created linear lesions
- 3
- Recurrences not related to previous pulsed field ablation (PFA) lesion creation
- 6
Safety
- No complications occurred
Original publication
Focal pulsed field ablation in complex atrial tachycardia: First clinical experience and 1-year outcome. Heart Rhythm. Published 15 July 2024. doi:10. 1016/ j. hrthm. 2024. 07. 024
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