Arrhythmias & electrophysiology

Focal pulsed field ablation in complex atrial tachycardia: First clinical experience and 1-year outcome

Heart RhythmPublished Retrospective cohort study

Authors' conclusion

Focal PFA of complex AT substrates was safe and efficient. Acute procedural success was 100%. After 1 year, the majority of patients were in sinus rhythm. A minority of recurrences was caused by insufficient PFA lesion creation.

Study context

Population
Patients with complex atrial tachycardia (AT), most (32/34) after ≥1 prior radiofrequency ablation, 2022–2023
Participants
34 patients
Outcome
Feasibility, safety and long-term outcome (recurrence of any AT)
Follow-up
Mean 340.9 ± 130.1 days
Methodological detailssingle-centre, consecutive patients, 51 linear lesions created and 12 pulmonary veins (re)isolated
  • Single-centre
  • Consecutive patients
  • 51 linear lesions created and 12 pulmonary veins (re)isolated

Main finding

As reported in the abstract

Acute procedural success in all patients

100%

Recurrence of any AT after mean follow-up of 340.9 ± 130.1 days

15 patients

44.1%

Observational data: associations, not effects.

Further findings

Procedural metrics

Mean procedural duration
102.7 ± 30.3 minutes
Left atrial dwell time
75.0 ± 24.7 minutes
Mean fluoroscopy duration
8.7 ± 5.3 minutes

Lesions created

Linear lesions
51
Pulmonary veins (re)isolated
12

Findings at reablation

Reablations
9
Gaps in previously created linear lesions
3
Recurrences not related to previous pulsed field ablation (PFA) lesion creation
6

Safety

No complications occurred

Original publication

Focal pulsed field ablation in complex atrial tachycardia: First clinical experience and 1-year outcome. Heart Rhythm. Published 15 July 2024. doi:10.1016/j.hrthm.2024.07.024

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