Heart failure & cardiomyopathies
Geriatric Nutritional Risk Index Predicts Bleeding Event in Patients with Heart Failure
Main finding · Bleeding eventsResult — go to the resultHazard ratio 1.952 95% CI 1.002–3.805Authors' conclusion
Heart failure patients with poor nutritional status, determined by GNRI under 106.2, experienced high bleeding event rates.
Study context
- Population
- Patients with HF
- Participants
- 2,044 patients
- Exposure
- Low Geriatric Nutritional Risk Index (GNRI) vs high GNRI
- Low GNRIn = 1,438
- High GNRIn = 606reference
- Outcome
- Composite of bleeding events (e.g. haemorrhagic stroke or gastrointestinal bleeding)
Main finding
Bleeding events
Hazard ratio
1.952
95% CI 1.002–3.805
P = 0.049
Low GNRIvs High GNRI
HR 1.952 (95% CI 1.002–3.805); P = 0.049
As reported in the abstract
- Bleeding event rates higher in low GNRI group (Kaplan-Meier)
- log-rank P < 0.001
Observational data: associations, not effects.
Further findings
Antiplatelet and anticoagulant use
- No differences between the two groups
Original publication
Geriatric Nutritional Risk Index Predicts Bleeding Event in Patients with Heart Failure. ESC Heart Fail. Published 20 December 2023. doi:10.
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