Heart failure & cardiomyopathies
Global Burden and Disparities in Pediatric Heart Failure: 1990-2021
Authors' conclusion
This study underscores the growing burden of PHF and the urgent need for targeted interventions to alleviate its impact.
Study context
- Population
- Children and young people aged 0–20 years with heart failure (HF) (pediatric heart failure (PHF)), worldwide, 1990–2021
- Outcome
- Prevalence, years lived with disability and estimated annual percentage changes of PHF
Methodological detailsstratified by age, gender, region, country and sociodemographic index
- Stratified by age, gender, region, country and sociodemographic index
Main finding
As reported in the abstract
Global prevalence of PHF · 2021
Global prevalence of PHF, cases
6.01 million
Global prevalence rate of PHF
228 per 100,000
Further findings
Change in PHF prevalence rate · 1990 to 2021
- Increase in prevalence rate
- 8.78%
- Significant differences by gender, age, country and region
Sociodemographic index and PHF prevalence
- Positive correlation
- P < 0.001
Leading causes of PHF
- Congenital heart anomalies, other cardiomyopathies, rheumatic heart disease and CKD, with varying trends over time
Years lived with disability · forecast to 2050
- Increase mirrored prevalence; consistent upward trend in PHF burden forecast by 2050
Original publication
Global Burden and Disparities in Pediatric Heart Failure: 1990-2021. JACC Heart Fail. Published 24 June 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →