Heart failure & cardiomyopathies
Global burden of heart failure in older adults: trends, socioeconomic inequalities, and future projections from 1990 to 2035
Authors' conclusion
Global heart failure burden in older adults is escalating fastest in low-middle SDI regions due to population growth and healthcare inequities.
Study context
- Population
- Older adults (aged ≥65 years) with heart failure (HF), global, 1990–2021
- Primary endpoint
- HF burden: prevalence, YLDs and underlying causes
- Follow-up
- 1990 to 2021
Methodological detailsdecomposition analysis, Bayesian Age-Period-Cohort projections to 2035
- Decomposition analysis
- Bayesian Age-Period-Cohort projections to 2035
Primary result
As reported in the abstract
Global HF burden in older adults
- Global HF cases increased (1990 to 2021)
- 14.1 million to 36.2 million
- Years lived with disability (YLDs) rose (1990 to 2021)
- 1.34 million to 3.45 million
- Contribution of population growth to increase in prevalence and YLDs
- 89.0%
- Ageing contribution, high-SDI regions
- −39.4%
- Ageing contribution, middle-SDI regions
- +28.7%
Further findings
Leading causes
- Ischaemic heart disease (leading cause)
- 37.6%
- Hypertensive heart disease
- 24.1%
Growth in HF burden, low-to-middle Sociodemographic Index (SDI) regions (fastest)
- EAPC
- 0.22
- Socioeconomic inequality widening over time
Projected age-standardised prevalence and YLDs · 2035
- Age-standardised prevalence
- 4935 cases per 100 000 population
- Age-standardised YLDs
- 473 years lived with disability per 100 000 population
Original publication
Global burden of heart failure in older adults: trends, socioeconomic inequalities, and future projections from 1990 to 2035. Eur Heart J Qual Care Clin Outcomes. Published 20 June 2025. doi:10.
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