Heart failure & cardiomyopathies
Guided implantation of a leadless left ventricular endocardial electrode and acoustic transmitter using computed tomography anatomy, dynamic perfusion and mechanics, and predicted activation pattern
Authors' conclusion
Preprocedural imaging and modeling data with intraprocedural guidance can successfully guide WiSE-CRT electrode and transmitter implantation to allow optimal AHR and adequate power delivery.
Study context
- Population
- Patients undergoing WiSE-CRT leadless LV endocardial electrode and acoustic transmitter implantation
- Participants
- 10 patients
- Exposure
- Biventricular pacing within computed tomography (CT)-identified target segments vs non-target segments
- Outcome
- AHR (maximal rate of LV pressure rise with biventricular pacing)
Main finding
As reported in the abstract
AHR with biventricular pacing
P < 0.001
Observational data: associations, not effects.
Further findings
Transmitter implanted within recommended site from preprocedural analysis
- Achieved in all patients
Segments per patient with wall thickness < 5 mm on CT
- Mean segments per patient with wall thickness < 5 mm
- 4.8 ± 3.5
Pacing in CT-identified scar
- Failure to capture or minimal acute hemodynamic response (AHR) improvement
Electrode implanted in TSs
- Electrode targeted to TSs in all patients; implanted in TSs
- 80%
Original publication
Guided implantation of a leadless left ventricular endocardial electrode and acoustic transmitter using computed tomography anatomy, dynamic perfusion and mechanics, and predicted activation pattern. Heart Rhythm. Published 13 July 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →