Hemodynamics of Exercise-Induced Hypertension and Relationship to Outcomes in Adults With Coarctation of the Aorta
Authors' conclusion
BP assessment during exercise can improve risk stratification and identify patients who may benefit from intensification of medical therapy.
Study context
- Population
- Adults with repaired coarctation of the aorta (COA) and healthy controlspatients with COA 41 · healthy controls 41
- Participants
- 41 vs 41
- Exposure
- COA vs healthy controls
- COAn = 41
- Healthy controlsn = 41
- Outcome
- Prevalence of EIH (systolic BP at peak exercise >210 mm Hg in men or >190 mm Hg in women)
- Follow-up
- Peak exercise
Main finding
As reported in the abstract
P = 0.004
Observational data: associations, not effects.
Further findings
| Outcome | Values |
|---|---|
| COA with EIH vs COA without EIH | COA without EIH 63% |
COA with exercise-induced hypertension (EIH) vs COA without EIH
- Those with EIH had higher arterial load at rest and during exercise, worse cardiac dysfunction, pulmonary congestion, and biomarkers of cardiovascular remodeling, despite no significant differences in resting systolic blood pressure (BP)
Original publication
Hemodynamics of Exercise-Induced Hypertension and Relationship to Outcomes in Adults With Coarctation of the Aorta. Circ Heart Fail. Published 5 March 2025. doi:10. 1161/ circheartfailure. 124. 012459
Summarised from the published abstract; every number is checked against it