Valvular & structural heart disease
Impact of age on outcomes after transcatheter aortic valve implantation
Authors' conclusion
Patients aged 80-89 and older than 90 undergoing TAVI have increased risk of readmission, complications, and mortality compared with patients younger than 70.
Study context
- Population
- Patients undergoing transcatheter aortic valve implantation (TAVI) for severe AS, Nationwide Readmissions Database, 2016–2018
- Participants
- 84,017 patients
- Exposure
- Age groups vs younger than 70
- Outcome
- Procedural complications, mortality and readmission
Methodological detailsnationwide database
- Nationwide database
Main finding
As reported in the abstract
Mortality
Each group vs <70Odds ratio (CI)P value
80-89
1.39(1.14–1.70)
P = 0.001>90
1.68(1.33–2.12)
P < 0.001Observational data: associations, not effects.
Further findings
| Outcome | HR (CI) | P value | |
|---|---|---|---|
| Overall readmission80-89vs <70 | 1.09 (1.03–1.14) | P = 0.001 | |
| Overall readmission>90vs <70 | 1.33 (1.25–1.41) | P < 0.001 | |
| 0.512Hazard ratio (log scale) |
Overall readmission
- Cardiac readmissions followed the same trend
Safety
Post-procedural stroke, AKI, pacemaker or ICD implantation
- Risk increased with incremental age grouping
Original publication
Impact of age on outcomes after transcatheter aortic valve implantation. Eur Heart J Qual Care Clin Outcomes. Published 9 May 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →