Impact of Eruptive vs Noneruptive Calcified Nodule Morphology on Acute and Long-Term Outcomes After Stenting
Main finding · TLFResult — go to the resultHazard ratio 2.07 95% CI 1.01–4.50Authors' conclusion
Compared with noneruptive CN morphology, lesions with an eruptive CN appearance on optical coherence tomography had a worse poststent long-term clinical outcome despite better acute stent expansion.
Study context
- Population
- Patients with target lesion calcified nodules on pre- and postintervention OCT undergoing stenting236 with calcified nodule (CNs)
- Participants
- 3,231 patients
- Exposure
- Eruptive CN vs noneruptive CN
- Eruptive CNn = 126
- Noneruptive CNn = 104reference
- Outcome
- Target lesion failure (TLF) (cardiac death, target vessel MI or clinically driven target lesion revascularization)
- Follow-up
- 2 years
Main finding
TLF
Hazard ratio
2.07
95% CI 1.01–4.50
P = 0.048
By group
Eruptive CNvs Noneruptive CN
HR 2.07 (95% CI 1.01–4.50); P = 0.048
As reported in the abstract
Observational data: associations, not effects.
Further findings
Target lesion revascularization · 2 years
P = 0.04
| Outcome | Eruptive CN | Noneruptive CN | P value |
|---|---|---|---|
| Stent expansionAdjusted for morphologic and procedural factors | 89.2% (SD 18.7%) | 81.5% (SD 18.9%) | P = 0.003 |
Original publication
Impact of Eruptive vs Noneruptive Calcified Nodule Morphology on Acute and Long-Term Outcomes After Stenting. JACC Cardiovasc Interv. Published 8 May 2023. doi:10.
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