Arrhythmias & electrophysiology

Inferior Sino-Atrial Node Exit Sites Are Associated With Electrical Remodeling

JACC Clin ElectrophysiolPublished Observational study

Authors' conclusion

SANi identified by high-resolution epicardial mapping were associated with extensive RA remodeling and are most likely due to altered sino-atrial conduction pathways.

Study context

Population
Patients with structural heart disease undergoing elective open-heart surgery, high-resolution epicardial mapping
Participants
27 patients
Exposure
Inferior vs superior sino-atrial node exit sites
  • SANin = 7
Outcome
Potential voltage in SAN area

Main finding

As reported in the abstract

P = 0.014

Observational data: associations, not effects.

Further findings

Total RA activation time

P = 0.046

Heart rate · preoperative and intraoperative

Heart rates comparable between groups, consistent preoperatively and intraoperatively

Original publication

Inferior Sino-Atrial Node Exit Sites Are Associated With Electrical Remodeling. JACC Clin Electrophysiol. Published 12 November 2025. doi:10.1016/j.jacep.2025.09.034

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.