Arrhythmias & electrophysiology
Intermuscular technique for implantation of the subcutaneous implantable defibrillator: a propensity-matched case–control study
Authors' conclusion
Our data showed the superiority of the IM S-ICD generator positioning in reducing device-related complications and inappropriate shocks.
Study context
- Population
- Patients undergoing subcutaneous implantable cardioverter defibrillator (S-ICD) implantation, 2013–2021matched cohort
- Participants
- 1,577 patients
- Exposure
- Intermuscular (IM) vs subcutaneous (SC) S-ICD generator positioning
- IMn = 290
- SCn = 290reference
- Outcome
- Survival from device-related complications and inappropriate shocks
- Follow-up
- Median 28 months
Methodological detailspropensity-score matched, consecutive patients
- Propensity-score matched
- Consecutive patients
Main finding
As reported in the abstract
Each group vs SCEstimate (95% CI)P value
IM
HR for device-related complications 0.41(0.17–0.99)
P = 0.041IM
HR for composite of complications and inappropriate shocks 0.50(0.30–0.86)
P = 0.013Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | P value | |
|---|---|---|---|
| Appropriate shocks | 0.90 (0.50–1.61) | P = 0.721 | |
| 0.512Hazard ratio (log scale) |
Interaction by gender, age, BMI, EF
- No significant interaction between generator positioning and gender, age, BMI or EF
Original publication
Intermuscular technique for implantation of the subcutaneous implantable defibrillator: a propensity-matched case–control study. Europace. Published 16 February 2023. doi:10.
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