Intraindividual Comparison of Ultrahigh-Spatial-Resolution Photon-Counting Detector Computed Tomography (CT) and Energy-Integrating Detector CT for Coronary Stenosis Measurement
Authors' conclusion
Compared with conventional EID-CT, UHR PCD-CT results in lower PDS values and more accurate stenosis measurements in coronary plaques with calcified components and leads to a substantial Coronary Artery Disease Reporting and Data System reclassification rate in 49.0% of patients.
Study context
- Population
- Patients with coronary calcification on EID-CT undergoing coronary CT angiography on both scanners within 30 days, April 2023–January 2024278 plaques
- Participants
- 49 patients
- Exposure
- UHR PCD-CT vs EID-CT for coronary stenosis measurement
- Outcome
- Percentage diameter stenosis (PDS) by plaque type
Methodological detailsPCD-CT acquired with same or lower CT dose index and equivalent contrast volume as EID-CT
- PCD-CT acquired with same or lower CT dose index and equivalent contrast volume as EID-CT
Main finding
As reported in the abstract
PDS by plaque type
| Group | Calcified percentage diameter stenosis (PDS) | Partially calcified PDS | Noncalcified PDS |
|---|---|---|---|
| PCD-CT | 45.1±20.7% | 44.3±19.6% | 39.1±15.2% |
| EID-CT | 54.6±19.2% | 54.9±20.0% | 39.0±16.0% |
Calcified percentage diameter stenosis (PDS)
PCD-CT45.1±20.7%
EID-CT54.6±19.2%
Partially calcified PDS
PCD-CT44.3±19.6%
EID-CT54.9±20.0%
Noncalcified PDS
PCD-CT39.1±15.2%
EID-CT39.0±16.0%
- PCD-CT vs EID-CT: P < 0.001 — calcified (202 plaques)
- PCD-CT vs EID-CT: P < 0.001 — partially calcified (51 plaques)
- PCD-CT vs EID-CT: P = 0.98 — noncalcified (25 plaques)
Observational data: associations, not effects.
Further findings
Mean difference
| Outcome | PCD-CT | EID-CT |
|---|---|---|
| Agreement of PDS with quantitative coronary angiography (subset: 12 patients, 56 lesions) | 7.3% (limits of agreement −10.7%/25.2%) | 17.4% (limits of agreement −6.9%/41.7%) |
- Reclassification to lower Coronary Artery Disease Reporting and Data System (CAD-RADS) with PCD-CT
- 49.0% · 24 events
- Reclassification to lower CAD-RADS with PCD-CT: of 49 patients
Agreement of PDS with quantitative coronary angiography (subset: 12 patients, 56 lesions)
- Higher agreement with quantitative coronary angiography for UHR PCD-CT
Original publication
Intraindividual Comparison of Ultrahigh-Spatial-Resolution Photon-Counting Detector CT and Energy-Integrating Detector CT for Coronary Stenosis Measurement. Circ Cardiovasc Imaging. Published 27 September 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →