Arrhythmias & electrophysiology
Left Atrial Reservoir Strain To Identify Advanced Atrial Cardiomyopathy in Patients With Atrial Fibrillation
Authors' conclusion
In patients with symptomatic AF, reduced LASr is associated with a more advanced atrial cardiomyopathy involving hemodynamic, mechanical and electrical atrial dyfsfunction. LASr may therefore provide a useful non-invasive marker of atrial cardiomyopathy in AF.
Study context
- Population
- Patients with symptomatic paroxysmal or persistent atrial fibrillation (AF) and preserved left ventricular (LV) ejection fraction scheduled for catheter ablationpatients enrolled
- Participants
- 91 patients
- Exposure
- Markers of LA cardiomyopathy compared between reduced LASr (<20%) and preserved LASr (≥20%)
- Reduced LASrn = 31
- Outcome
- Age
Main finding
As reported in the abstract
P < 0.001
Observational data: associations, not effects.
Further findings
Female
P = 0.007
LA compliance · lower with reduced LASr
P < 0.001
LA pressure · higher with reduced LASr
P = 0.031
LA voltage · lower with reduced LASr
P < 0.01
NT-proBNP · higher with reduced LASr
P < 0.001
LA volumes · larger with reduced LASr
P < 0.001
Original publication
Left Atrial Reservoir Strain To Identify Advanced Atrial Cardiomyopathy in Patients With Atrial Fibrillation. Heart Rhythm. Published 22 October 2026. doi:10.
Summarised from the published abstract; every number is checked against it