Valvular & structural heart disease

Lifetime exercise dose and ventricular arrhythmias in patients with mitral valve prolapse

EuropacePublished Retrospective cohort study

Authors' conclusion

We found no clear association between moderate lifetime exercise dose and severe VA in patients with MVP.

Study context

Population
Patients with mitral valve prolapse (MVP)61% female
Participants
136 patients
Exposure
Severe VA vs no severe VA
  • Severe VAn = 17
Outcome
Association of lifetime exercise dose (MET h/week) with severe VA

Main finding

As reported in the abstract

Lifetime exercise dose

P = 0.34

Observational data: associations, not effects.

Further findings

Lifetime exercise dose > 9.6 metabolic equivalents of task (MET) h/week as marker for severe VA

OR (95% CI)P value
> 9.6 MET h/weekUnadjusted; borderline significant3.38 (0.92–12.40)P = 0.07
> 9.6 MET h/weekAdjusted for age2.63 (0.66–10.56)P = 0.17

Circumstances at VA event

Wakeful rest
53%
Exercise
29%
Sleep
12%

Original publication

Lifetime exercise dose and ventricular arrhythmias in patients with mitral valve prolapse. Europace. Published 18 October 2023. doi:10.1093/europace/euad309

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