Arrhythmias & electrophysiology
Long-Term Freedom From Ventricular Arrhythmias in Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) With Endocardial Only Ablation: Predictors of Success
Authors' conclusion
Long-term VT-free survival can be achieved in over half of ARVC patients following ENDO-only VT ablation, increasing to over 75% if VT noninducibility is achieved.
Study context
- Population
- Patients with ARVC (Task Force Criteria) undergoing first endocardial-only ventricular tachycardia (VT) ablation, 1998–2020
- Participants
- 74 patients
- Outcome
- Freedom from any recurrent sustained VT after the last endocardial (ENDO)-only ablation
Methodological detailsconsecutive patients
- Consecutive patients
Main finding
As reported in the abstract
Freedom from any recurrent sustained VT after last ENDO-only ablation · median follow-up 6.6 years (Q1-Q3: 3.4-11.2 years)
Patients free from any VT recurrence
40
54.1%
Additional patients with rare VT (≤2 episodes)
12.2%
Observational data: associations, not effects.
Further findings
VT noninducibility after ablation
- VT noninducibility achieved
- 49 (66%)
VT-free survival among patients with noninducibility · long-term follow-up
- VT-free survival with noninducibility
- 75.5%
Predictors of VT-free survival (multivariable analysis)
- >45 y of age at diagnosis, HR
- 0.41 (0.17-0.98) (95% CI)
- VT noninducibility, HR
- 0.36 (0.16-0.80) (95% CI)
- Multivariable analysis
Original publication
Long-Term Freedom From Ventricular Arrhythmias in ARVC With Endocardial Only Ablation: Predictors of Success. JACC Clin Electrophysiol. Published 16 May 2024. doi:10. 1016/ j. jacep. 2024. 05. 003
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