Arrhythmias & electrophysiology
Long-term outcomes after catheter ablation for idiopathic atypical atrial flutter
Authors' conclusion
IAAFL in patients had distinct electrophysiologic features suggestive of atrial cardiomyopathy. These patients are at risk for development of cardiovascular adverse events after ablation.
Study context
- Population
- Patients undergoing catheter ablation for atrial flutterof 180 ablated for AFL
- Participants
- 89 patients
- Exposure
- IAAFL vs C-AFL after catheter ablation
- IAAFLn = 22
- C-AFLn = 67reference
- Outcome
- Composite of:
- CV death
- Ischemic stroke
- Hospitalization for worsening HF
- Follow-up
- 3.5 ± 2.8 years
Main finding
As reported in the abstract
IAAFL vs C-AFLHazard ratio (95% CI)P value
IAAFL
3.45(1.20–9.89)
P = 0.015Multivariable analysis
4.14(1.21–14.07)
P = 0.02Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | P value | |
|---|---|---|---|
| Primary outcome, multivariable analysis (independent associations)Brain natriuretic peptide levels, per 1 pg/mL | 1.01 (1.00–1.01) | P = 0.01 | |
| Primary outcome, multivariable analysis (independent associations)IAAFLvs C-AFL | 4.14 (1.21–14.07) | P = 0.02 | |
| 0.050.21520Hazard ratio (log scale) |
- Atrial scar in IAAFL
- 22 · events
- Atrial scar in IAAFL: observed in all 22 IAAFL patients
Electrophysiologic study, sinus rhythm
- Significantly longer intra-atrial conduction time and lower atrial voltage in IAAFL vs C-AFL
Original publication
Long-term outcomes after catheter ablation for idiopathic atypical atrial flutter. Heart Rhythm. Published 12 April 2024. doi:10.
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