Long-Term Outcomes After Fontan Conversion Operation: A Comparative Analysis Based on Type of Fontan Connection
Authors' conclusion
Duration of Fontan physiology rather than the type of Fontan connection may be the main determinant of outcomes.
Study context
- Population
- Adults with Fontan palliation
- Participants
- 534 adults
- Exposure
- Atriopulmonary Fontan vs Fontan conversion to total cavopulmonary connection (TCPC) vs initial TCPC
- Atriopulmonary Fontann = 199
- FC-TCPCn = 138
- TCPCn = 197
- Outcome
- Death/transplant (transplant-free survival)
Main finding
As reported in the abstract
Death/transplant · 15 years
P = 0.8
Observational data: associations, not effects.
Further findings
| Outcome | Atriopulmonary Fontan | FC-TCPC | TCPC | P value | |
|---|---|---|---|---|---|
| 15-year death/transplant excluding operative mortality · 15 yearsFC-TCPC vs TCPC | Not reported in the abstract | 38% | Not reported in the abstract | P = 0.3 | Atriopulmonary Fontan, TCPC: not reported in the abstract |
| Operative mortality of FC | Not reported in the abstract | 8% | Not reported in the abstract | Atriopulmonary Fontan, TCPC: not reported in the abstract |
Risk factors for death/transplant (multivariable)
- Older age, hepatorenal dysfunction, HF and higher Fontan pressures
Original publication
Long-Term Outcomes After Fontan Conversion Operation: A Comparative Analysis Based on Type of Fontan Connection. Circ Heart Fail. Published 13 October 2025. doi:10.
Summarised from the published abstract; every number is checked against it