Valvular & structural heart disease
Long-term survival after transcatheter aortic valve implantation (TAVI) in low-flow, low-gradient aortic valve stenosis
Authors' conclusion
However, after adjustment for possible baseline confounders, a low-flow status per se did not have an impact on long-term mortality after TAVI.
Study context
- Population
- Patients undergoing TAVI with a hypothetical minimum 5-year follow-up73% HG-AS, 15% pLFLG-AS, 11% cLFLG-AS
- Participants
- 574 patients
- Exposure
- cLFLG-AS and pLFLG-AS vs HG-AS after TAVI
- Outcome
- All-cause mortality
Methodological detailssingle-centre, propensity score-weighted
- Single-centre
- Propensity score-weighted
Main finding
As reported in the abstract
All-cause mortality (long-term survival)
- Unadjusted: cLFLG-AS worst long-term prognosis, rapid survival decrease within first year; pLFLG- and HG-AS similar survival
- p=0.023
Observational data: associations, not effects.
Further findings
Baseline EF and long-term mortality
- Baseline EF not related to long-term mortality
Post-TAVI left ventricular ejection fraction (LVEF) improvement >10%
- Patients with post-TAVI LVEF improvement >10% lived significantly longer
- P = 0.02
Original publication
Long-term survival after TAVI in low-flow, low-gradient aortic valve stenosis. EuroIntervention. Published 18 November 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →