Acute cardiac care & resuscitation
Management Patterns and Outcomes of Invasive Mechanical Ventilation in Patients With Cardiogenic Shock
Authors' conclusion
In this cohort, patients were frequently on minimal ventilator support within 24 hours of intubation, yet spontaneous breathing trials and extubation were delayed due to hemodynamic instability. Rates of failed extubation were comparable to other forms of critical illness.
Study context
- Population
- Patients treated for cardiogenic shock requiring invasive mechanical ventilation at an academic safety net hospital, 2017–2023
- Participants
- 104 patients
- Outcome
- Invasive mechanical ventilation (IMV) management and outcomes
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
- Intubation for ongoing cardiac arrest
- 37%
- Intubation for hypoxic respiratory failure
- 32%
- FiO2 24 h after intubation, median
- 40% [IQR: 30%-50%]
- PEEP 24 h after intubation, median
- 5 cm H2O [IQR: 5-8]
- Spontaneous breathing trials delayed
- 78%
- Delay due to hemodynamic instability
- 82%
- Nonpalliative extubation
- 62%
- Time to extubation, median
- 4.8 days (IQR: 2.3-8.0)
- Received temporary mechanical circulatory support (tMCS)
- 49%
- tMCS removed before extubation (tMCS survivors)
- 98%
- Reintubation within 48 h
- 14%
- In-hospital mortality
- 41%
Observational data: associations, not effects.
Original publication
Management Patterns and Outcomes of Invasive Mechanical Ventilation in Patients With Cardiogenic Shock. JACC Adv. Published 23 July 2025. doi:10.
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