Arrhythmias & electrophysiology
Moderate/Severe Biatrial Dilation Predicts Adverse Events After Ablation in Atrial Fibrillation with Heart Failure
Authors' conclusion
AF patients with HFpEF had better long-term outcomes than those with HFr-mrEF, and moderate/severe biatrial dilation could predict adverse clinical events following catheter ablation in AF and HF patients.
Study context
- Population
- Atrial fibrillation (AF) patients with heart failure (HF) who underwent successful ablation
- Participants
- 1,402 patients
- Exposure
- HFpEF vs HFr-mrEF after AF ablation
- Outcome
- Adverse clinical events:
- All-cause death
- HF hospitalization
- Stroke
- Follow-up
- 42 ± 15 months
Methodological detailsconsecutively enrolled
- Consecutively enrolled
Main finding
As reported in the abstract
Cumulative incidence of adverse clinical events
P < 0.001
- Patients with adverse clinical events after ablation (overall)
- 265 (18.9%)
Observational data: associations, not effects.
Further findings
All-cause death
P = 0.011
HF hospitalization
P < 0.001
Independent predictors of adverse clinical events (multivariate)
| HR (95% CI) | P value | ||
|---|---|---|---|
| Non-paroxysmal AF | 1.922 (1.130–3.268) | P = 0.016 | |
| LAD ≥ 45 mm | 2.197 (1.206–4.003) | P < 0.001 | |
| LVEF | 0.959 (0.946–0.981) | P < 0.001 | |
| RAD ≥ 45 mm | 2.044 (1.362–3.238) | P < 0.001 | |
| 0.20.5125Hazard ratio (log scale) |
Predictive model (non-paroxysmal AF, LAD ≥ 45 mm, RAD ≥ 45 mm)
- AUC
- 0.728 (95% CI 0.696-0.760, P < 0.001)
Original publication
Moderate/Severe Biatrial Dilation Predicts Adverse Events After Ablation in Atrial Fibrillation with Heart Failure. ESC Heart Fail. Published 17 June 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →