Coronary disease & ACSCohort study
Mortality Trends After Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction
- Registry-based cohort study
- Western Denmark Heart Registry
- Danish national health registries
Authors' conclusion
In a high-income European country with a fully implemented pPCI strategy, 1-year mortality in pPCI-treated patients with STEMI decreased substantially between 2003 and 2018. Approximately three-quarters of the absolute mortality reduction occurred within the first 30 days after pPCI.
Study context
- Population
- First-time percutaneous coronary intervention (PCI)-treated patients undergoing primary PCI for STEMI in Western Denmark, 2003 to 2018
- Participants
- 19,613 patients
- Exposure
- Time-interval groups by year of primary PCI (pPCI)
- Outcome
- 1-year mortality
- Follow-up
- 1 year
Main finding
As reported in the abstract
Adjusted hazard ratio
0.71
95% CI 0.62–0.82
By group
2015-2018 vs 2003-2006
adjusted HR 0.71 (95% CI 0.62–0.82)
Observational data: associations, not effects.
Further findings
0–30-day mortality
- Largest absolute mortality decline; absolute reduction
- 2.3%
31–365-day mortality
- Risk reduction
- 1.0%
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Mortality Trends After Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction. J Am Coll Cardiol. Published 5 September 2023. doi:10.1016/j.jacc.2023.06.025
Summarised from the published abstract; every number is checked against it