Three-dimensional cardiac magnetic resonance allows the identification of slow-conducting anatomical isthmuses in tetralogy of Fallot
Authors' conclusion
3D late gadolinium enhancement cardiac magnetic resonance can identify SCAI with excellent accuracy and may refine non-invasive risk stratification and patient selection for invasive EAM in tetralogy of Fallot.
Study context
- Population
- Consecutive patients with repaired tetralogy of Fallot who underwent right ventricular electroanatomical mapping (RV-EAM) and 3D-LGE-CMRderivation 48
- Comparison
- 3D-LGE-CMR vs invasive RV electroanatomical mapping (reference) and proposed risk scores
- Outcome
- Diagnostic performance of 3D-LGE-CMR to non-invasively identify slow-conducting anatomical isthmuses (SCAI)
Methodological detailsderivation and validation cohorts
- Derivation and validation cohorts
Performance
As reported in the abstract
Identification of SCAI or blocked anatomical isthmus
| Test or model | AUC | Sensitivity (derivation) | Sensitivity (validation) | Specificity (derivation) | Specificity (validation) |
|---|---|---|---|---|---|
| 3D-LGE-CMR | — not stated in the abstract | 100% | 95% | 90% | 91% |
| Risk scores | ≤ .68 | — not stated in the abstract | — not stated in the abstract | — not stated in the abstract | — not stated in the abstract |
AUC
3D-LGE-CMR— not stated in the abstract
Risk scores≤ .68
Sensitivity (derivation)
3D-LGE-CMR100%
Risk scores— not stated in the abstract
Sensitivity (validation)
3D-LGE-CMR95%
Risk scores— not stated in the abstract
Specificity (derivation)
3D-LGE-CMR90%
Risk scores— not stated in the abstract
Specificity (validation)
3D-LGE-CMR91%
Risk scores— not stated in the abstract
— not stated in the abstract
Original publication
Three-dimensional cardiac magnetic resonance allows the identification of slow-conducting anatomical isthmuses in tetralogy of Fallot. Eur Heart J. Published 15 May 2024. doi:10.
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