Arrhythmias & electrophysiology
Multipolar radiofrequency ablation: Early experience with a novel approach to target intramural ventricular arrhythmias
Authors' conclusion
MPA may facilitate arrhythmia control in patients with intramural VAs. Nevertheless, additional studies are necessary to better evaluate MPA safety and efficacy profiles, with further preclinical work and larger clinical studies required.
Study context
- Population
- Patients with refractory ventricular arrhythmias with evidence of intramural origin by defined mapping criteria, treated with multipolar ablation (MPA)consecutive patients who underwent 36 MPA procedures · MPA procedures for premature ventricular contractions 20 · MPA procedures for ventricular tachycardia 16
- Participants
- 31 patients
- Outcome
- MPA lesion delivery
Methodological detailsconsecutive patients
- Consecutive patients
Main finding
As reported in the abstract
- MPA lesions delivered
- 151
- Radiofrequency ablation (RFA)
- 60 s
- Power
- 22 W
- Initial current
- 379 mA
- Impedance drop
- 19 Ω
Observational data: associations, not effects.
Further findings
Technical limitations of lesion delivery
- High impedance in coronary sinus branches
- Char formation on return electrodes
Success
Cases
- Acute success
- 34 (94%)
- Near-term success
- 25 (69%)
- Long-term success
- 23 (70%)
Original publication
Multipolar radiofrequency ablation: Early experience with a novel approach to target intramural ventricular arrhythmias. Heart Rhythm. Published 7 August 2025. doi:10. 1016/ j. hrthm. 2025. 08. 005
Composed by AI from the published abstract and checked against it. How Briefs are made →