Arrhythmias & electrophysiology
Nationwide burden of sudden cardiac death among patients with a psychiatric disorder
Authors' conclusion
In this study, the rate of SCD in patients with psychiatric disorders is higher across all age groups than in the general population. Having a psychiatric disorder is independently associated with SCD. Patients with schizophrenic disease had the highest rates of SCD.
Study context
- Population
- Danish residents aged 18–90 years in 201045,703 deaths, 6002 sudden cardiac death (SCD)
- Participants
- 4.3 million residents
- Exposure
- Psychiatric disorder vs general population
- Outcome
- Incidence of SCD
Methodological detailssystematic review of all deaths in 1 year, death certificates and autopsy reports
- Systematic review of all deaths in 1 year
- Death certificates and autopsy reports
Main finding
As reported in the abstract
SCD
Each group vs general populationHazard ratio (CI)P value
Psychiatric disorderadjusted for age, sex and comorbidities
2.31(2.19–2.43)
P < 0.001Schizophrenic disordershighest HR
4.51(3.95–5.16)
P < 0.001- Psychiatric disorder · range across age groups; age dependent
- IRR 1.79-6.45; P < 0.001
Observational data: associations, not effects.
Further findings
- Share of excess life years lost caused by SCD, age 18-40 with psychiatric disorder
- 13%
- Expected 10-year excess loss of life, 18-year-olds with psychiatric disorder
Original publication
Nationwide burden of sudden cardiac death among patients with a psychiatric disorder. Heart. Published 22 October 2024. doi:10.
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