Prevention & lipids

Native T1 mapping times are strongly influenced by elite athlete status

Eur Heart J Cardiovasc ImagingPublished Cross-sectional analysis

Authors' conclusion

Elite athletes have lower native T1 compared with non-athletes, both in women and men. Athlete- and sex-specific reference ranges should be applied when interpreting native T1 in athlete populations, especially in female athletes.

Study context

Population
Elite athletes (≥16 years; ≥10 h of exercise/week) and healthy non-athletic controls undergoing cardiovascular magnetic resonance imaging on a 1.5 tesla MRI machine
Participants
240 vs 80
Exposure
Native T1 between elite athletes and healthy non-athletic controls
  • Elite athletesn = 240
  • Non-athlete healthy controlsn = 80
Outcome
Native T1
Methodological detailsage-matched
  • Age-matched

Main finding

As reported in the abstract

P < 0.001

Observational data: associations, not effects.

Further findings

OutcomeElite athletesNon-athlete healthy controls
Native T1, by sex
Male953 ms ±19968 ms ±16
Female968 ms ±20999 ms ±25
  • Native T1, by sex: male athletes vs. controls P < 0.001
  • Native T1, by sex: female athletes vs. controls P < 0.001

Independent determinants of native T1 (multivariate linear regression)

Elite athlete status β
−13.34
Heart rate β
0.6
Average left-ventricular wall thickness β
−8.28
Native blood pool T1 β
0.09
Adjusted R2
51.4%
  • Each P < 0.001

Original publication

Native T1 mapping times are strongly influenced by elite athlete status. Eur Heart J Cardiovasc Imaging. Published 18 April 2025. doi:10.1093/ehjci/jeaf123

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