Valvular & structural heart disease
New-Onset Right Bundle Branch Block (RBBB) After Transcatheter Aortic Valve Replacement: Incidence and Risk Factors for Permanent Pacemaker Implantation
Authors' conclusion
Post-TAVR new-onset RBBB is a rare phenomenon that is associated with high rates of further conduction system deterioration and need for PPI, occurring mostly within 1 week post-TAVR.
Study context
- Population
- Patients with new-onset RBBB after transcatheter aortic valve replacement (TAVR)
- Participants
- 7,782 TAVR procedures
- Outcome
- Incidence of post-TAVR new-onset RBBB and risk factors for PPI need
Methodological detailsmulticentre, 7 Israeli centres, consecutive procedures
- Multicentre
- 7 Israeli centres
- Consecutive procedures
Main finding
As reported in the abstract
Incidence of new-onset RBBB
Patients with new-onset RBBB
41
Incidence per 1,000 TAVR procedures
5.3
95% CI 3.8–7.1
Observational data: associations, not effects.
Further findings
Prediction of API by PR
Specificity
Sensitivity
Permanent pacemaker implantation (PPI) among new-onset RBBB · 1 year post-TAVR
- Underwent PPI
- 19 (46.3%)
- Had absolute pacing indication (API) (high-grade AV block or alternating bundle branch block)
- 15 (36.6%)
- API after discharge (late AV block)
- 1
Overall survival, no PPI vs PPI
- Nonsignificantly better survival without PPI
Original publication
New-Onset RBBB After Transcatheter Aortic Valve Replacement: Incidence and Risk Factors for Permanent Pacemaker Implantation. JACC Clin Electrophysiol. Published 6 August 2025. doi:10.
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