Coronary disease & ACS

Ongoing Opioid Treatment and Symptoms of Myocardial Infarction in Calls to the Emergency Medical Services

JACC AdvPublished Retrospective cohort study

Authors' conclusion

In calls to the Emergency Medical Services, opioid treatment initiated prior to the onset of MI was associated with less frequent chest pain in MI.

Study context

Population
Calls to the Copenhagen EMS, Denmark, 2014–2018, followed by hospitalization and an myocardial infarction (MI) diagnosis
Participants
6,633 calls
Exposure
Ongoing opioid treatment vs no opioid treatment
  • Opioid treatmentn = 552
  • Controlsn = 6,081reference
Outcome
MI symptoms and time from call to hospitalization

Main finding

Chest pain

Adjusted odds ratio

0.70

95% CI 0.57–0.85

By group

Opioid treatmentvs Controls
adjOR 0.70 (95% CI 0.57–0.85)

As reported in the abstract

Observational data: associations, not effects.

Original publication

Ongoing Opioid Treatment and Symptoms of Myocardial Infarction in Calls to the Emergency Medical Services. JACC Adv. Published 19 September 2024. doi:10.1016/j.jacadv.2024.101268

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