Coronary disease & ACSCohort study
Severe mental illness, chest pain, and emergency response
- Registry-based cohort study
Authors' conclusion
Prehospital triage of chest pain did not contribute substantially to inequity in cardiovascular care of patients with SMI, whereas care disparities were observed in hospitalization, diagnostics, and treatment.
Study context
- Population
- First-time chest pain-related calls to the Copenhagen Emergency Medical Services (emergency number and out-of-hours service), 2014–2018
- Participants
- 64,937 chest pain-related calls
- Exposure
- Patients with severe mental illness (SMI) vs controls without SMI
- SMIn = 4,303
- Controlsn = 60,634reference
Main finding
Acute ambulance dispatch
Odds ratio
1.24
95% CI 1.16–1.32
By group
SMI vs Controls
OR 1.24 (95% CI 1.16–1.32)
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | SMI | Controls | OR (95% CI) | |
|---|---|---|---|---|
| Admission within 24 h after the call | 81% | 85% | 0.82 (0.76–0.89) | |
| CV diagnosis during hospitalization following the call | 16% | 26% | 0.61 (0.56–0.67) | |
| Revascularization within 30 days after the call | 4% | 7% | 0.65 (0.55–0.78) | |
| 30-day mortality | 1% | 2% | 1.18 (0.90–1.55) | |
| 0.512Odds ratio (log scale) |
30-day mortality
- Similar in patients with SMI and controls
Original publication
Severe mental illness, chest pain, and emergency response. Eur J Prev Cardiol. Published 24 November 2025. doi:10.1093/eurjpc/zwaf745
Summarised from the published abstract; every number is checked against it