Coronary disease & ACS

Time From Distress Call to Percutaneous Coronary Intervention and Outcomes in Myocardial Infarction

JACC AdvPublished Registry-based cohort study

Authors' conclusion

The risk of recurrent myocardial infarction, death, and heart failure following PCI treatment of STEMI increases rapidly when delay exceeds 1 hour.

Study context

Population
Patients admitted with STEMI in Copenhagen, Denmark (2014–2018) who called emergency services ≤72 hours before percutaneous coronary intervention (PCI)1,735 called ≤12 hours
Participants
1,822 patients
Exposure
Time from distress call to PCI
  • ≤120 minutesn = 1,196reference
  • >120 minutesn = 420
Outcome
Combined death, recurrent MI or HF
Follow-up
30 days and 1 year

Main finding

As reported in the abstract

Combined endpoint, 1-year cumulative incidence

Observational data: associations, not effects.

Further findings

Standardized 30-day combined outcome · 30 days — >120 minutes
11.1% (95% CI 8.39%–14.2%)
  • Standardized 30-day combined outcome: <60 minutes 7.33% (95% CI 5.41%–9.63%)
  • Standardized 30-day combined outcome: standardized to the STEMI population (multivariate logistic regression)

Original publication

Time From Distress Call to Percutaneous Coronary Intervention and Outcomes in Myocardial Infarction. JACC Adv. Published 3 June 2024. doi:10.1016/j.jacadv.2024.101005

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