Time From Distress Call to Percutaneous Coronary Intervention and Outcomes in Myocardial Infarction
Authors' conclusion
The risk of recurrent myocardial infarction, death, and heart failure following PCI treatment of STEMI increases rapidly when delay exceeds 1 hour.
Study context
- Population
- Patients admitted with STEMI in Copenhagen, Denmark (2014–2018) who called emergency services ≤72 hours before percutaneous coronary intervention (PCI)1,735 called ≤12 hours
- Participants
- 1,822 patients
- Exposure
- Time from distress call to PCI
- ≤120 minutesn = 1,196reference
- >120 minutesn = 420
- Outcome
- Combined death, recurrent MI or HF
- Follow-up
- 30 days and 1 year
Main finding
As reported in the abstract
Combined endpoint, 1-year cumulative incidence
Observational data: associations, not effects.
Further findings
- Standardized 30-day combined outcome · 30 days — >120 minutes
- 11.1% (95% CI 8.39%–14.2%)
- Standardized 30-day combined outcome: <60 minutes 7.33% (95% CI 5.41%–9.63%)
- Standardized 30-day combined outcome: standardized to the STEMI population (multivariate logistic regression)
Original publication
Time From Distress Call to Percutaneous Coronary Intervention and Outcomes in Myocardial Infarction. JACC Adv. Published 3 June 2024. doi:10. 1016/ j. jacadv. 2024. 101005
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