Acute cardiac care & resuscitation
Outcomes With Peripheral Venoarterial Extracorporeal Membrane Oxygenation for Suspected Acute Myocarditis: 10-Year Experience From the Extracorporeal Life Support Organization Registry
Authors' conclusion
Compared with all-comers supported with VA-ECMO, in-hospital mortality for patients with acute myocarditis is significantly lower, with nearly two-thirds of patients surviving to discharge.
Study context
- Population
- Adults with suspected acute myocarditis on peripheral venoarterial extracorporeal membrane oxygenation (VA-ECMO), ELSO registry 2011–2020myocarditis cohort
- Participants
- 850 adults
- Exposure
- Suspected acute myocarditis vs all-comers receiving VA-ECMO
- Myocarditisn = 850
- Outcome
- In-hospital mortality
Methodological detailsmulticentre registry (ELSO)
- Multicentre registry (ELSO)
Main finding
As reported in the abstract
P < 0.001
Observational data: associations, not effects.
Secondary outcomes
Risk factors for in-hospital mortality (multivariable)
- Earlier year of support, older age, higher weight, Asian race, need for extracorporeal CPR, sepsis, and lower mean arterial pressure and pH before ECMO
Safety
ECMO complications (bleeding, limb ischemia, infections, ischemic stroke)
- More common among nonsurvivors; significantly declined during the study period
Original publication
Outcomes With Peripheral Venoarterial Extracorporeal Membrane Oxygenation for Suspected Acute Myocarditis: 10-Year Experience From the Extracorporeal Life Support Organization Registry. Circ Heart Fail. Published 22 June 2023. doi:10. 1161/ circheartfailure. 122. 010152
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