Heart failure & cardiomyopathies
Poor in-hospital congestion improvement in acute heart failure patients classified according to left ventricular ejection fraction: prognostic implications
Authors' conclusion
In AHF, the degree of congestion reduction assessed over the in-hospital stay period can stratify the subsequent event risk. Limited reduction in both clinical congestion and B-lines number are related to poor prognosis, irrespective of HF subtype.
Study context
- Population
- Patients admitted for acute HF, classified by left ventricular ejection fraction (LVEF) (95 HFrEF, 57 HF with mildly reduced EF, 92 HFpEF)
- Participants
- 244 patients
- Exposure
- Limited vs more sizeable in-hospital decongestion
- Outcome
- Composite of:
- All-cause mortality
- HF re-hospitalization
Methodological detailstwo European tertiary care centres
- Two European tertiary care centres
Main finding
As reported in the abstract
Limited improvement vs Sizeable decongestionHazard ratio (95% CI)P value
Clinical congestion score
2.33(1.51–3.61)
P = 0.0001NP levels
2.29(1.55–3.38)
P < 0.0001Number of B-lines
6.44(4.19–9.89)
P < 0.001Observational data: associations, not effects.
Further findings
Adjusted analysis
- Same pattern of association after adjusting for confounding factors
Primary outcome, by LVEF category (subgroup)
- Limited improvement in clinical congestion score and number of B-lines related to poor prognosis in all LVEF categories
Original publication
Poor in-hospital congestion improvement in acute heart failure patients classified according to left ventricular ejection fraction: prognostic implications. Eur Heart J Cardiovasc Imaging. Published 13 March 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →