Heart failure & cardiomyopathies
Predicting all-cause mortality by means of a multisensor implantable defibrillator algorithm for heart failure monitoring
Authors' conclusion
The HeartLogic algorithm provides an index that can be used to identify patients at higher risk for all-cause mortality. The index state identifies periods of significantly increased risk of death.
Study context
- Population
- Implantable cardioverter-defibrillator (ICD) patients with the HeartLogic heart failure (HF) monitoring feature activated, 26 centres
- Participants
- 568 patients26 centres
- Exposure
- IN-alert vs OUT of alert state
- Outcome
- All-cause mortality
- Follow-up
- Median 26 months
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
Death
IN-alert vs OUT of alertEstimate (95% CI)P value
Death
IRR 13.72(7.62–25.60)
P < 0.001Adjusted for age, ischemic cardiomyopathy, kidney disease, AF
HR 9.18(5.27–15.99)
P < 0.001- Deaths during follow-up
- 55
Observational data: associations, not effects.
Further findings
Alerts · median follow-up 26 months
- Alerts recorded
- 1200
- Patients with alerts
- 370 (65%)
- Time IN-alert, % of total observation
- 13% (151/1159 years)
- Time IN-alert, % of follow-up in patients with alerts
- 20%
Original publication
Predicting all-cause mortality by means of a multisensor implantable defibrillator algorithm for heart failure monitoring. Heart Rhythm. Published 24 March 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →