Predictive Accuracy of Magnetocardiography for Diagnosing Myocardial Ischemia in NSTE-ACS Patients With Residual Post-PCI Angina
Authors' conclusion
The OPM-MCG model provides a reliable, noninvasive, and quick tool for identifying post-PCI angina in NSTE-ACS patients, highlighting its clinical value for risk stratification, guiding personalized pharmacologic therapy, and follow-up strategies.
Study context
- Population
- NSTE-ACS patients who underwent PCI with pre- and post-PCI optically pumped magnetometer magnetocardiography (OPM-MCG) scansNSTE-ACS patients who underwent PCI
- Participants
- 363 patientsEvents: 134 (36.9%)
- Predictors
- OPM-MCG model incorporating five Δ parameters
- Predicted outcome
- post-PCI angina (Seattle Angina Questionnaire angina frequency score <100 at 3 months)
Methodological detailsstratified bootstrap least absolute shrinkage and selection operator regression (1,000 iterations), 10-fold cross-validation
- Stratified bootstrap least absolute shrinkage and selection operator regression (1,000 iterations)
- 10-fold cross-validation
Model performance
As reported in the abstract
Area under curve
Average during bootstrapping
0.85(95% CI 0.78-0.93)
Final model with 10-fold cross-validation
0.79(95% CI 0.78-0.80)
Further findings
Characteristics of patients with post-PCI angina
- Patients with post-PCI angina had higher body mass index, more frequent history of PCI, and greater use of oral nitrates
Original publication
Predictive Accuracy of Magnetocardiography for Diagnosing Myocardial Ischemia in NSTE-ACS Patients With Residual Post-PCI Angina. JACC Adv. Published 19 August 2025. doi:10.
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