Valvular & structural heart disease

Prognostic impact of regurgitant volume to left atrial volume ratio on ventricular functional mitral regurgitation

Eur Heart J Cardiovasc ImagingPublished multicentre prospective registry

Main finding · Heart failure hospitalizationResult — go to the resultHazards ratio 1.25 95% CI 1.03–1.52

Authors' conclusion

The RVol/LAV ratio might serve as a valuable metric for improving risk stratification in patients with VFMR.

Study context

Population
Patients with ventricular functional mitral regurgitation (VFMR) undergoing transcatheter edge-to-edge repair (M-TEER)patients who underwent M-TEER
Participants
1,830 patients
Exposure
Low regurgitant volume (RVol)/left atrial volume (LAV) vs high RVol/LAV
  • Low RVol/LAVn = Eight hundred eighty-eight
  • High RVol/LAVn = 942
Outcome
Heart failure hospitalization
Follow-up
3 years after repair

Main finding

As reported in the abstract

Hazards ratio

1.25

95% CI 1.03–1.52

P = 0.022

Events by group

Low RVol/LAV vs high RVol/LAV
hazards ratio 1.25 (95% CI 1.03–1.52); P = 0.022

Observational data: associations, not effects.

Further findings

Median RVol/LAV ratio · baseline

Median value of the RVol/LAV ratio
0.40

Original publication

Prognostic impact of regurgitant volume to left atrial volume ratio on ventricular functional mitral regurgitation. Eur Heart J Cardiovasc Imaging. Published 6 November 2025. doi:10.1093/ehjci/jeaf304

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.