Heart failure & cardiomyopathies
Prognostic implication of lung ultrasound in heart failure: a pooled analysis of international cohorts
Authors' conclusion
A higher number of B lines in patients with HF was associated with an increased risk of morbidity and mortality, regardless of the clinical setting.
Study context
- Population
- Patients with heart failure (HF) at hospital admission, at discharge, or in outpatient clinicsadmission 578, discharge 389, outpatient 980
- Participants
- 1,947 patients
- Comparison
- Highest vs lowest tertile of lung ultrasound (LUS) B-line count
- Outcome
- Composite of:
- Rehospitalization for HF
- All-cause death
Methodological detailsmulticentre, B-line count by the eight-zone LUS scanning protocol
- Multicentre
- B-line count by the eight-zone LUS scanning protocol
Pooled result
As reported in the abstract
Primary outcome by B-line tertile
Tertile 3 vs Tertile 1Adjusted hazard ratio (CI)P value
At discharge
5.74(3.26–10.12)
P < 0.0001Outpatients
2.66(1.08–6.54)
P = 0.033Further pooled results
Effect modification by age and left ventricular ejection fraction (LVEF)
- Age and LVEF did not influence the prognostic capacity of LUS in different clinical settings
Incremental value over MAGGIC and AHEAD scores
- Adding B-line count improved net reclassification significantly in all three clinical settings
Original publication
Prognostic implication of lung ultrasound in heart failure: a pooled analysis of international cohorts. Eur Heart J Cardiovasc Imaging. Published 12 April 2024. doi:10.
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