Prognostic implications of left ventricular torsion measured by feature-tracking cardiac magnetic resonance in patients with ST-elevation myocardial infarction
Authors' conclusion
LV torsion measured by CMR is closely associated with the prognosis of STEMI and would be a promising indicator to improve patients' risk stratification.
Study context
- Population
- ST-elevation myocardial infarction (STEMI) patients with cardiovascular magnetic resonance (CMR) within 1 week after timely primary PCI
- Participants
- 420 patients
- Exposure
- Reduced vs preserved left ventricular (LV) torsion by feature-tracking CMR
- Outcome
- MACCE
- Follow-up
- Median 52 months
Methodological detailsregistry
- Registry
Main finding
As reported in the abstract
median 52 months
P < 0.001
- MACCE risk per 0.1°/cm reduction in LV torsion, adjusted for clinical or CMR parameters respectively
- 1.125- or 1.092-fold
Observational data: associations, not effects.
Further findings
1-year LV remodelling
P < 0.001
| Outcome | P value |
|---|---|
| LV torsion, STEMI vs healthy controls | P < 0.001 |
| LV torsion, with vs without MACCE | P < 0.001 |
- 1-year LV remodelling — Risk per 0.1°/cm reduction in LV torsion, adjusted for clinical or CMR parameters respectively
- 1.110- or 1.082-fold
- LV torsion, STEMI vs healthy controls: STEMI 1.04 °/cm
- LV torsion, STEMI vs healthy controls: Healthy controls 1.63 °/cm
- LV torsion, with vs without MACCE: MACCE 0.79 °/cm
- LV torsion, with vs without MACCE: No MACCE 1.08 °/cm
Incremental value over LVEF and infarct size
- Adding LV torsion improved risk classification for MACCE and LV remodelling
Predictors of reduced LV torsion
- Tobacco use, worse post-PCI flow and greater microvascular obstruction size were presumptive risk factors
Original publication
Prognostic implications of left ventricular torsion measured by feature-tracking cardiac magnetic resonance in patients with ST-elevation myocardial infarction. Eur Heart J Cardiovasc Imaging. Published 3 September 2022. doi:10.
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