Valvular & structural heart disease
Prognostic value of left ventricular myocardial work indices in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement
Performance · All-cause mortalityResult — go to the resultHazard ratio 0.639 95% CI 0.463–0.883Authors' conclusion
LV GWI is independently associated with all-cause mortality in patients undergoing TAVR and has a higher prognostic value compared to both conventional and advanced parameters of LV systolic function.
Study context
- Population
- Patients with severe aortic stenosis (AS) undergoing transcatheter aortic valve replacement (TAVR)64 died
- Participants
- 281 patients
- Outcome
- All-cause mortality
- Follow-up
- Median 52 (IQR 41-67) months
Performance
As reported in the abstract
Hazard ratio
0.639
95% CI 0.463–0.883
P = 0.007
LV GWI (per-tertile increase)
HR 0.639 (95% CI 0.463–0.883); P = 0.007
Per-tertile increase, as printed
Further findings
Baseline left ventricular (LV) myocardial work indices · before TAVR
- LV GWI mean ± SD
- 1872 ± 753 mmHg%
- GCW mean ± SD
- 2240 ± 797 mmHg%
- GWW median (IQR)
- 200 (IQR 127-306) mmHg%
- GWE median (IQR)
- 89 (IQR 84-93)%
Original publication
Prognostic value of left ventricular myocardial work indices in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement. Eur Heart J Cardiovasc Imaging. Published 6 July 2023. doi:10. 1093/ ehjci/ jead157
Composed by AI from the published abstract and checked against it. How Briefs are made →