Valvular & structural heart disease
Prognostic value of modified model for end-stage liver disease scores in patients with significant tricuspid regurgitation
Authors' conclusion
Both MELD-XI and MELD-Albumin scores provided incremental prognostic information and could play important roles in risk assessment in patients with significant TR.
Study context
- Population
- Patients with at least moderate pure native tricuspid regurgitation (TR), China Valvular Heart Disease study, April–June 2018
- Participants
- 1,825 patients
- Exposure
- Prognostic value of MELD-XI and MELD-Albumin scores
- Outcome
- All-cause death
- Follow-up
- Within 2 years
Methodological detailsChina Valvular Heart Disease study
- China Valvular Heart Disease study
Main finding
As reported in the abstract
Deaths during follow-up
165
9.0%
MELD-XI and MELD-Albumin scores (continuous or categorized) independently associated with 2-year mortality
all adjusted P < 0.001
MELD-XI score: net reclassification index over model without hepatorenal indexes
0.237 (0.138-0.323) (95% CI)
MELD-Albumin score: net reclassification index over model without hepatorenal indexes
0.220 (0.122-0.302) (95% CI)
Observational data: associations, not effects.
Further findings
Subgroups (incl. patients under medical treatment, normal LVEF)
- Results similar in clinically meaningful subgroups
Original publication
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