Cardio-oncology & other

Psychological Distress and Cardiovascular Health in Pregnancy: Findings From the U.S. National Health Interview Survey

JACC AdvPublished cross-sectional analysis

Authors' conclusion

We observed a strong association between psychological distress and suboptimal CVH during pregnancy, highlighting the need to manage psychological health along with CVH in pregnant individuals.

Study context

Population
Pregnant participants aged ≥18 years in the U.S. National Health Interview Survey (2013–2018)pregnant individuals (representing >1.5 million pregnant individuals each year of the survey)
Participants
1,110 participants
Exposure
Associations between severe psychological distress and cardiovascular health (CVH)
Outcome
Prevalence of psychological distress

Main finding

As reported in the abstract

Observational data: associations, not effects.

Further findings

OutcomeAdjusted rate ratio (95% CI)P value
CVH score (7-item Life's Essential 8; higher scores indicated worse CVH)Moderate psychological distressvs mild or no psychological distress1.25 (1.13–1.38)P < 0.001
CVH score (7-item Life's Essential 8; higher scores indicated worse CVH)Severe psychological distressvs mild or no psychological distress1.42 (1.20–1.68)P < 0.001
  • CVH score (7-item Life's Essential 8; higher scores indicated worse CVH): lower CVH scores compared to those with mild or no psychological distress
  • CVH score (7-item Life's Essential 8; higher scores indicated worse CVH): lower CVH scores compared to those with mild or no psychological distress
  • CVH score (7-item Life's Essential 8; higher scores indicated worse CVH): Multivariable Poisson regression adjusting for age, race/ethnicity, sexual orientation, education level, family income, any known cardiovascular conditions, and insurance

CVH score (7-item Life's Essential 8; higher scores indicated worse CVH)

A stepwise relation was observed between the severity of psychological distress and CVH

Original publication

Psychological Distress and Cardiovascular Health in Pregnancy: Findings From the U.S. National Health Interview Survey. JACC Adv. Published 25 April 2025. doi:10.1016/j.jacadv.2025.101683

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