Heart failure & cardiomyopathies
Psychosocial Factors Partially Explain Gender Differences in Health-Related Quality of Life in Heart Failure Patients
Authors' conclusion
In this study, we have shown that the gap in health-related QoL between men and women with chronic heart failure can be partially explained by the interaction between biological and psychosocial factors.
Study context
- Population
- Consecutive patients with chronic HF, recruited 2004–2014
- Participants
- 1,236 patients
- Exposure
- Women vs men
- Outcome
- Health-related QoL (Minnesota Living with Heart Failure Questionnaire (MLHFQ))
Methodological detailssingle-centre, observational
- Single-centre
- Observational
Main finding
As reported in the abstract
MLHFQ overall summary score (higher = worse QoL)
Female
49
± 23
Male
43
± 24
P < 0.001
Observational data: associations, not effects.
Further findings
Female gender as predictor of quality of life (QoL), by model adjustment
- Univariate and clinically adjusted models: female gender predicted worse global, physical and emotional QoL and better social QoL
- Psychosocial-only and comprehensive (psychosocial + clinical) models: gender differences no longer significant
Original publication
Psychosocial Factors Partially Explain Gender Differences in Health-Related Quality of Life in Heart Failure Patients. ESC Heart Fail. Published 29 December 2022. doi:10.
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