Valvular & structural heart disease
Pulmonary artery pulsatility index in patients with tricuspid valve regurgitation: a simple non-invasive tool for risk stratification
Authors' conclusion
In patients with greater than or equal to moderate TR with and without PH, lower PAPi is associated with right ventricular dysfunction, right heart failure, and worse survival.
Study context
- Population
- Patients with ≥ moderate TR (any aetiology) with pulmonary artery (PA) systolic and diastolic pressures on first echocardiogram
- Participants
- 5,079 patients
- Exposure
- Pulmonary hypertension (PH) vs no PH; Pulmonary artery pulsatility index (PAPi) levels
- PHn = 2,741
- Outcome
- All-cause mortality
- Follow-up
- 5 years
Main finding
As reported in the abstract
- PH and decreasing PAPi associated with larger RV, worse RV systolic function, higher NT-pro BNP, greater right HF and worse survival
Observational data: associations, not effects.
Further findings
PAPi distribution
- Median PAPi
- 3.0 (IQR 1.9, 4.4)
Correlation of non-invasive vs invasive PA pressures and PAPi (echo and right heart catheterization within 24 h subset)
- Correlation very good
- r = 0.76
Original publication
Pulmonary artery pulsatility index in patients with tricuspid valve regurgitation: a simple non-invasive tool for risk stratification. Eur Heart J Cardiovasc Imaging. Published 25 April 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →