Arrhythmias & electrophysiology
Rates and predictors for sustained ventricular tachycardia in patients with cardiac sarcoidosis and AV block as first cardiac presentation: Implications for device implantation
Authors' conclusion
Patients with CS presenting with AVB have a high risk of sustained VA.
Study context
- Population
- Patients with cardiac sarcoidosis without prior ventricular arrhythmias (VA)82 analysed after excluding VA
- Participants
- 112 patients
- Exposure
- AV block vs other symptoms as first cardiac presentation of cardiac sarcoidosis
- Atrioventricular block (AVB)n = 34
- OSFn = 48reference
- Outcome
- Sustained VA
- Follow-up
- During
Main finding
As reported in the abstract
P = 0.001
Observational data: associations, not effects.
Further findings
LGE
P = 0.966
Abnormal PET uptake
P = 0.007
| Outcome | AVB | OSF | P value |
|---|---|---|---|
| Death, LVAD implantation or heart transplantation | 11.8% | — not stated in the abstract | P = 0.847 |
— not stated in the abstract
Predictors of VA (multivariate analysis)
HR
- AVB
- 25.15
- Right ventricular (RV) late gadolinium enhancement (LGE) on cardiovascular magnetic resonance (CMR)
- 7.39
- Immunosuppressive therapy (less VA)
- 0.26
Original publication
Rates and predictors for sustained ventricular tachycardia in patients with cardiac sarcoidosis and AV block as first cardiac presentation: Implications for device implantation. Heart Rhythm. Published 14 September 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →